Manufacturing Process of Top-Quality Paracetamol Oral Suspension Drops (150mg) by Den Mark Pharmaceuticals Pvt. Ltd.
Den Mark Pharmaceuticals Pvt. Ltd. is committed to producing top-quality pharmaceutical products following the guidelines set by the World Health Organization (WHO) Good Manufacturing Practices (GMP).
Paracetamol is a member of the class of drugs known as analgesics, or painkillers. It is used to treat mild to severe pain, including aches and pains throughout the body, headaches, migraines, nerve pain, toothaches, sore throats, and menstrual pain. It's also used to treat cold and flu symptoms. It can also be used to lower a fever or elevate a high temperature in the body.
Here is a comprehensive overview of the manufacturing process for Paracetamol Oral Suspension Drops(150mg) and Syrup:
1. Raw Material Procurement
The first step is sourcing high-quality raw materials. Den Mark Pharmaceuticals ensures that all raw materials meet stringent quality standards, including Paracetamol active ingredient, solvents, flavours, and preservatives. Suppliers are carefully selected and undergo thorough quality checks.
2. Weighing and Dispensing:
Precise measurements of raw materials are crucial. The Paracetamol active ingredient is accurately weighed and then mixed with appropriate solvents in a designated mixing vessel. This ensures uniform distribution of the active ingredient throughout the solution.
3. Heating and Dissolution:
The mixture undergoes controlled heating to facilitate the dissolution of the Paracetamol and other ingredients. This step ensures that all components are completely dissolved and homogenized.
4. Filtration:
The dissolved solution is passed through a series of filters to remove any impurities or undissolved particles. This filtration process ensures the purity of the final product.
5. Sterilization:
The filtered solution is sterilized using validated methods, such as heat sterilization or filtration through sterile membranes. This step is crucial for ensuring the product's safety and efficacy.
6. Filling and Packaging:
Once sterilized, the Paracetamol solution is filled into sterile containers, such as amber glass bottles for oral drops or plastic bottles for syrup. Accurate filling machines are used to ensure precise dosing of the medication.
7. Sealing and Labelling:
The containers are sealed using tamper-evident seals to maintain product integrity after filling. Labels containing essential information such as dosage instructions, expiry date, and batch number are affixed to the containers.
8. Quality Control:
Rigorous quality control measures are implemented throughout the manufacturing process. Samples are taken at various stages for testing to ensure compliance with specifications for purity, potency, and microbiological safety.
9. Stability Testing:
Finished Paracetamol Oral Suspension Dropsundergo stability testing to assess their shelf-life under various storage conditions. This ensures that the product remains effective and safe throughout its intended lifespan.
10. Packaging and Distribution:
Once quality control and stability testing are completed, the Paracetamol Oral Suspension Dropsand Syrup are packaged into secondary packaging for shipment. Den Mark Pharmaceuticals ensures that proper storage and distribution practices are followed to maintain product quality until it reaches the end consumer.
Conclusion:
By adhering to WHO GMP guidelines and implementing stringent quality control measures at every step of the manufacturing process, Den Mark Pharmaceuticals Pvt. Ltd., known for affordable medicines in India, ensures the production of top-quality Paracetamol Oral Drops(150mg), meeting the highest standards of safety, efficacy, and reliability.