enquire now
Manufacturing Process of High-Quality Calcium Citrate + Vitamin D3 + Zinc + Magnesium Tablets by Den Mark Pharmaceuticals Pvt. Ltd.

Den Mark Pharmaceuticals Pvt. Ltd. adheres strictly to the WHO GMP guidelines to ensure the production of top-quality Calcium Citrate + Vitamin D3 + Zinc + Magnesium Tablets.

Here's a comprehensive overview of our manufacturing process:

  • Raw Material Procurement and Quality Control: We source raw materials from approved suppliers who meet stringent quality standards. Calcium citrate, Vitamin D3, Zinc, and Magnesium undergo thorough quality checks to ensure purity, potency, and compliance with pharmacopeial standards.
  • Granulation Process: a. Mixing: Precisely measured quantities of Calcium citrate, Vitamin D3, Zinc, and Magnesium are mixed with suitable excipients like binders and disintegrants in a blender. b. Wet Granulation: The blend is moistened with a binder solution and granulated to form uniform granules. c. Drying: The wet granules are dried to remove moisture, ensuring stability and preventing microbial growth.
  • Tablet Compression: a. Lubrication: Granules are lubricated to enhance flow properties and prevent sticking during compression. b. Compression: The lubricated granules are compressed into tablets of specified size, shape, and weight using high-quality tablet presses.
  • Coating (Optional): Tablets may undergo coating to improve appearance, taste masking, or to provide enteric protection. Coating materials are carefully selected for compatibility and functionality.
  • Quality Control Testing: Throughout manufacturing, samples are collected and subjected to rigorous quality control tests. These include assays for active ingredients, dissolution testing, hardness testing, and visual inspection for defects.
  • Packaging: a. Primary Packaging: Finished tablets are packed into blister packs or bottles under controlled conditions to maintain product integrity. b. Secondary Packaging: Labeled blister packs or bottles are placed into cartons with appropriate labelling and patient information inserts.
  • Storage and Distribution: Finished Pharmaceutical products are stored in controlled environments with appropriate temperature and humidity conditions to maintain stability. Strict inventory management and distribution practices ensure timely customer delivery while preserving product quality
  • Documentation and Record Keeping: Comprehensive documentation of all pharmaceutical manufacturing processes, quality control tests, and deviations is maintained per WHO GMP guidelines. This includes batch records, certificates of analysis, and validation reports.
  • Cleaning and Sanitization: Equipment used in manufacturing is regularly cleaned and sanitized to prevent cross-contamination and ensure product safety.
  • Continuous Improvement: Den Mark Pharmaceuticals Pvt. Ltd. is committed to continuous improvement through regular audits, training programs, and best practices to enhance product quality and compliance with WHO GMP guidelines.

By following these clean pharmaceutical manufacturing processes and adhering to WHO GMP guidelines, Den Mark Pharmaceuticals Pvt. Ltd ensures the production of top-quality Calcium Citrate + Vitamin D3 + Zinc + Magnesium Tablets that meet the highest standards of safety, efficacy, and regulatory compliance.