We at Den Mark Pharmaceuticals manufacture Top-quality Pharmaceutical Products which includes Paracetamol + Diclofenac tablets following the World Health Organization (WHO) Good Manufacturing Practices (GMP) guidelines. To ensure consistent production of safe and effective Paracetamol + Diclofenac tablets, We take into account following steps:
1. Raw Material Procurement:
Den Mark Pharmaceuticals sources high-quality raw materials for Paracetamol and Diclofenac from approved suppliers with proper documentation and compliance records. Each batch of raw materials undergoes thorough testing and validation to ensure purity, potency, and absence of contaminants.
2. Granulation :
The manufacturing process begins with the granulation of Paracetamol and Diclofenac. The measured quantities of both active pharmaceutical ingredients (APIs) are mixed with excipients such as lactose, starch, and microcrystalline cellulose. This blend is then granulated using a suitable binder solution to form granules of uniform size.
3. Blending :
The granules of Paracetamol and Diclofenac are then blended with additional excipients, including disintegrants, lubricants, and glidants, in a blending machine. The blending process ensures the homogeneity of the mixture, which is critical for dose uniformity and efficacy.
4. Compression :
Optionally, the tablets may undergo a coating process to improve stability, taste masking, or visual appeal. The coating formulation is prepared according to approved process and applied using specialized equipment under controlled conditions.
5. Coating (Optional) :
Optionally, the tablets may undergo a coating process to improve stability, taste masking, or visual appeal. The coating formulation is prepared according to approved process and applied using specialized equipment under controlled conditions.
6. Quality Control :
Den Mark Pharmaceuticals conducts rigorous quality control checks at various stages throughout the manufacturing process. Samples are collected and analyzed for parameters such as hardness, friability, disintegration time, and assay of active ingredients. Any deviations from specifications are promptly addressed to maintain product quality and compliance.
7. Packaging :
Once the tablets pass quality control tests, they are packaged in blister packs or bottles using automated packaging equipment. The packaging materials are selected to ensure protection against environmental factors and tampering while maintaining product integrity.
8. Labeling and Serialization :
Each package is affixed with labels containing essential information such as product name, dosage strength, batch number, expiry date, and manufacturer details. Additionally, serialization codes are applied for traceability and authenticity verification in compliance with regulatory requirements.
9. Storage and Distribution :
The finished Paracetamol + Diclofenac tablets are stored in designated warehouses under controlled temperature and humidity conditions. Strict inventory management protocols are followed to prevent mix-ups and ensure timely distribution to wholesalers and pharmacies.
Conclusion : Den Mark Pharmaceuticals Pvt. Ltd. employs a systematic and quality-driven approach in manufacturing Paracetamol + Diclofenac tablets, adhering to WHO GMP guidelines at every step. We are Custom Pharmaceutical Manufacturing company delivering top-quality pharmaceutical products trusted by healthcare professionals and patients by prioritizing quality control, regulatory compliance, and patient safety.
